surrogate vnt  (GenScript corporation)

Journal: Transboundary and Emerging Diseases

Article Title: Serological screening in wild ruminants in Germany, 2021/2022: No evidence of SARS‐CoV‐2, bluetongue virus or pestivirus spread but high seroprevalences against Schmallenberg virus

doi: 10.1111/tbed.14600

Figure Lengend Snippet: Proportion of samples per German federal state (left) and per wild ruminant species (right) that reacted positive (red) in an receptor‐binding domain‐based severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) antibody ELISA. In the lower right panel, the number of sero‐reactive results/number of analysed samples is given separately for each federal state and, if known, the hunting district from which the samples originated. The serum that additionally tested positive in a surrogate virus neutralisation test is framed in red. BY–Bavaria, HE–Hesse, MV–Mecklenburg‐Western Pomerania, NW–North Rhine‐Westphalia, RP–Rhineland‐Palatinate

Article Snippet: Wildlife samples that reacted positive in the RBD‐ELISA were subsequently tested by a virus neutralisation test (VNT) against the SARS‐CoV‐2 strain 2019_nCoV Muc‐IMB‐1 performed as described previously (Schlottau et al., ) and by a surrogate VNT (cPass SARS‐CoV‐2 Surrogate VNT Kit, GenScript).

Techniques: Binding Assay, Enzyme-linked Immunosorbent Assay, Virus, Western Blot

Journal: Vaccines

Article Title: Immunogenicity after Second ChAdOx1 nCoV-19 (AZD1222) Vaccination According to the Individual Reactogenicity, Health Status and Lifestyle

doi: 10.3390/vaccines9121473

Figure Lengend Snippet: Relationship between the immunogenicity assays in 79 participants who are full vaccinated with AZD1222 ( a ) value of S/Co of anti-S1 antibody and sVNT (%) ( b ) Spots of Discovery SARS-CoV-2 kit S1 panel and sVNT. S/Co; signal to cut-off, sVNT; surrogate virus neutralization test.

Article Snippet: Therefore, we utilized the cPASS SARS-CoV-2 neutralizing antibody detection kit, surrogate VNT, sVNT (Genscript Biotech Corporation, Piscataway, NJ, USA), which is known to have a high correlation with the PRNT [ , ].

Techniques: Immunopeptidomics, Virus, Neutralization